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Drug ReportsAntithrombin alfa
Atryn(antithrombin alfa)
ATryn (antithrombin alfa) is a protein pharmaceutical. Antithrombin alfa was first approved as Atryn on 2006-07-28. It has been approved in Europe to treat antithrombin III deficiency.
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Events Timeline
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FDA approval date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
hemic and lymphatic diseasesD006425
hereditary congenital and neonatal diseases and abnormalitiesD009358
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
Reference product - 351(a)
Reference product - 351(a)
Interchangeable product - 351(k)
Interchangeable product - 351(k)
Biosimilar product - 351(k)
Biosimilar product - 351(k)
Antithrombin (recombinant)
Tradename
Proper name
Company
Number
Date
Products
AtrynAntithrombin (Recombinant)rEVO BiologicsA-125284 DISCN2009-02-06
2 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
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HCPCS
No data
Clinical
Clinical Trials
91 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Antithrombin iii deficiencyD020152—D68.591—21—4
ThrombophiliaD019851—D68.59———1—1
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Pre-eclampsiaD011225EFO_0000668O14——1——1
ThrombosisD013927————1——1
Venous thrombosisD020246—I82.40——1——1
Indications Phases 2
No data
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Cardiopulmonary bypassD002315——1————1
HemorrhageD006470MP_0001914R581————1
Postoperative hemorrhageD019106——1————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameAntithrombin alfa
INNantithrombin alfa
Description
Antithrombin-III precursor (ATIII) (PRO0309)
Classification
Protein
Drug class—
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID—
RxCUI—
ChEMBL IDCHEMBL1201554
ChEBI ID—
PubChem CID—
DrugBank—
UNII IDAWV6I5L6H2 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 906 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
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17 adverse events reported
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